Other areas, including Pembrokeshire and parts of the north coast will not be affected, maps suggest.
The south west of England between Plymouth and Penzance will also swerve the white stuff, as well as most of East Anglia and the area above Luton.
Birmingham, Worcester, Stoke, Liverpool, Manchester, Leeds, Newcastle and the Scottish borders are included in the snow zone, as well as London, the wider south east and the south coast of England.
But most of the north east coast will not be snowed on, according to WXCharts.
The Met Office has said that more snow and ice could hit the UK later this week.
Experts think that this could be as much as between two and five centimetres, which may affect a fairly wide area.
It comes after the UK was buffeted by snow at the weekend, and, last night, the country experienced its coldest night of winter so far, as -13.3°C was recorded in Loch Glascarnoch in Scotland.
The Met Office’s Chief Meteorologist, Frank Saunders, has said that adverse conditions are set to affect areas in all four parts of the UK this evening.
He said: “Hail, sleet or snow showers are expected to affect parts of Scotland and Northern Ireland, spreading to Wales and parts of northwest England this evening, before moving into part of southwest England, the Midlands and southern England during the early hours of Tuesday.
“Rain or hail is more likely towards some western coasts.
“Icy stretches which develop overnight as a result of these showers, or the recent wet conditions, could bring some disruption to travel.
“In addition to the ice, we could see snow accumulations of a few cm above 200 metres, with a chance of greater than 5 cm above 200 metres in Wales.
“The heaviest snow showers may also produce temporary accumulations of 0-2 cm at low levels.
“It is not possible to say exactly where this snow might fall, so it’s important that people are prepared.”
Forecasters have also said that there is the potential for another frontal system to move in from the southwest on Wednesday, bringing further snow and ice.
A yellow warning is currently in place to cover this.
Met Office Deputy Chief Meteorologist, Mike Silverstone, explained: “There is a chance of a further spell of rain, sleet and snow moving in from the southwest on Wednesday to affect some southern parts of the UK.”
“Whilst not all those in the warning area may be affected, it is possible that that 2-5 cm of snow may accumulate fairly widely. Whether this system will brush the south of the UK or miss us altogether still remains a little uncertain, but we’ll continue to assess this over the next day or two. Weather warnings may well be updated, so it’s important people stay up to date with the forecast.”